News
Do you want to stay up to date with the latest BHD news? This is the place to be!
Here we will let you know about the latest BHD research, events, and opportunities to get involved with our work.
BHD Case Reports: Summer Round-Up
Every few months we highlight some of the recent case reports of Birt-Hogg-Dubé syndrome (BHD). A case report is a detailed account of (normally) a single person's diagnosis and treatment journey. In this blog, we present 3 cases of BHD and cancer.
Can Cigarette Smoking Cause Loss of Folliculin?
In people with BHD, smoking is not thought to impact lung cyst formation or lung function. However, it is not clear whether smoking and COPD affect FLCN function, the gene that is mutated in BHD.
Does Gender Affect when you are Diagnosed with BHD?
On average it takes 5 years for a rare disease to be diagnosed. A recent study from Germany also suggests gender may play a role in how quickly someone is diagnosed with BHD.
How Common are Genetic Causes of Kidney Cancer?
Kidney cancer is the 6th most common cancer in the developed world. Many genetic conditions are linked with kidney cancer including BHD.
How Does Loss of FLCN Lead to Kidney Cancer?
Birt-Hogg-Dubé syndrome is associated with an increased risk of kidney cancer. It is important to understand how kidney cancer can develop so we can know how to best treat it.
Monitoring and Treating Inherited Kidney Cancer
Recently several papers have been published about kidney cancer that are relevant to Birt-Hogg-Dubé syndrome. In this blog, we summarise the papers and share what we can learn from them.
New Techniques to Understand BHD Kidney Cancer
A study looked at different inherited kidney cancers includeing BHD at a single cell level. This means looking at the individual cells that make up the cancer.
Should People Who Have a Collapsed Lung be Tested for BHD?
A new study has been published looking at the prevalence of BHD among people who have a collapsed lung for no apparent reason.
What Tuberous Sclerosis Complex can teach us about BHD
Tuberous sclerosis complex is a rare inherited condition. It shares some features with BHD. Here, we compare Tuberous sclerosis complex and BHD.
BHD Syndrome at a Rare Lung Disease Clinic in China
The first study of BHD in China was published in 2008. However, by the end of 2021 there were only 221 Chinese patients reported. In 2019, a Rare Lung Disease Clinic was set up at The First Affiliated Hospital of USCT in Anhui province, China.
How Common is BHD? A study in a Healthcare System Population
The prevalence of Birt-Hogg-Dubé syndrome is currently unknown. Some reports have estimated the prevalence to be 1 in 200,000 people, but this is likely an underestimate of the true figure.
How does Folliculin Regulate mTORC1 Activity?
Our cells need to be able to sense and respond to our body’s needs. Mechanistic target of rapamycin complex 1 (mTORC1) is a protein in our cells that acts as a central hub for this sensing ability. Why is this relevant to BHD?